Roasted Butternut Squash and Brussels Sprouts are crispy and flavorful. This brussels sprouts recipe has all the holiday flavors that you crave in one side dish!
Next time try Steamed Brussels Sprouts - delicious every time!

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Why you'll love this recipe
Brussels sprouts are a great side dish for your holiday meal. They are a healthy and simple side that pairs well with most meals.
You'll love this combination brussel sprouts, cranberries, and butternut squash recipe all in one!
Ingredients

For the exact measurements, please refer to the printable recipe card at the bottom of this post.
- butternut squash - I prefer to buy butternut squash that has been peeled, sliced and diced. It's just so much work!
- brussels sprouts
- olive oil
- Italian seasoning mix - if you'd prefer you could substitute ranch seasoning mix, or even use a teaspoon of salt with half a teaspoon black pepper.
- pecans - walnuts or hazelnuts would be delicious as well!
- dried cranberries - dried blueberries would be another great substitution.
Instructions

This is an overview of the instructions for the Roasted Butternut Squash and Brussels Sprouts. For the complete directions just scroll down to the bottom!
- Preheat oven.
- Peel and dice the butternut squash (if you didn't buy it already diced), Clean sprouts, remove any outer leaves that are brown. Slice Brussels sprouts.
- Add vegetables to a large mixing bowl. Add the olive oil and toss with Italian dressing mix.
- Place brussels sprouts and squash on pan. Spread the vegetables out in one even layer on a rimmed baking sheet. Place the sprouts cut side down.
- Bake in the preheated, roast until fork tender.
- Remove from the oven. Top with pecans and cranberries. Serve and enjoy!
Equipment
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FAQ's
Technically yes, but the squash will not come out as crispy. I really recommend using fresh butternut squash for this recipe.
I don't recommend making this ahead, but you can prep the veggies the day before and then bake when are you ready to enjoy your holiday meal.
Look for brussels sprouts that are firm. Also, smaller brussels sprouts are sweeter and more tender.
Roasted Brussels sprouts should be crispy on the edges and fork-tender in the center.

Tips
- Making this dish for your Thanksgiving menu? Line your baking sheet for foil or parchment paper for easy clean up!
- If your brussels sprouts are large quarter them instead of halving them. Roasted brussels sprouts are delicious when they are crispy and caramelized.
- For crispy vegetables, make sure they are completely dry so they don't steam. Blot them with paper towels. Additionally, spread them out on the sheet pan in one even layer.
- Roasting them at high temperature will make them caramelize and roast perfectly!
Variations
Want to change up the flavors of this recipe?
- Use roasted butternut squash seeds, roasted pumpkin seeds or sunflower seeds in place of the pecans.
- A balsamic glaze or a drizzle of maple syrup is super yummy! Both are great options.
- Switch out the Italian dressing for garlic powder and parmesan cheese.
- Add a pinch of red pepper flakes to make them spicy!
- Add sliced red onion or shallot for a light onion flavor.
- Finish your vegetables with a squeeze of fresh lemon juice or a balsamic vinegar glaze for a zesty flavor.
- Add a generous drizzle of pure maple syrup
- Top with crispy bacon - everything is better with bacon!

Storage
Store: Allow the veggies to cool to room temperature. Store leftovers in the fridge in an airtight container for up to four days.
Freeze: Freeze leftovers in a freezer-safe bag for up to 12 months. Freezing will slightly change the texture of your roasted vegetables.
Reheat: For best results reheat leftovers at 350 degrees in the oven for 5 to 7 minutes. You can also reheat in the microwave for 30 seconds to a minute.
Related recipes
I'm a big fan of a great side dish - here are more of my favorites!
- If you love brussels sprouts check out this sauteed brussels sprouts recipe.
- Southern Collard Greens with Ham - this easy side is a delicious dish! The perfect side dish for your holiday table.
- Here's another great Thanksgiving side dish recipe. Buttered Rutabagas are filled with savory flavor. We love them this time of year!
- Love green vegetables? Then you don't want to miss this 3 Ingredient Green Beans recipe.
- These lovely Asparagus Puff Pastry Bundles make the prettiest presentation, not to mention they taste AMAZING!
You can check out all of my favorite vegetable and side dish Thanksgiving recipes here!
Serve with
- Start your meal with this easy recipe for Panera Butternut Squash Soup.
- Save on extra dishes and try this Crockpot Turkey and Stuffing recipe.
- You can't have brussel sprouts without this creamy mashed potatoes recipe.
- These rolls from frozen bread dough are soft and yeast and are delicious with every meal.
- Candied Sweet Potatoes is another comforting recipe for your holiday meal.
- You can't have a meal without dessert so give this butter cake recipe a try. This recipe is so good. Rich and dense butter cake - be sure to serve it with a scoop of vanilla ice cream!
Don't forget to check out my Amazon storefront for some of my favorite products! 🛍️
If you love this recipe please leave a ⭐⭐⭐⭐⭐ rating!
Butternut Squash and Brussel Sprouts Recipe
Ingredients
- 4 cups butternut squash
- 3 cups brussels sprouts
- ¼ cup olive oil
- 1 tablespoon Italian seasoning mix
- ½ cup pecans
- ¼ cup dried cranberries
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Instructions
- Preheat oven to 400 degrees. Place parchment paper on baking sheet, set aside.
- Peel and dice the butternut squash into one inch pieces.
- Clean Brussels sprouts and cut in half.
- Add the brussel sprouts and raw squash to a large bowl. Add the olive oil and toss with Italian dressing mix.
- Spread the vegetables in a single layer baking sheet. Place halved brussels sprouts cut side down on lined baking sheet.
- Place in the hot oven. Bake 25 minutes shaking once about halfway through the cooking process. Roasting at high heat will help the caramelize.
- Remove from the oven. Top the brussels sprouts with crunchy pecans and sweet tart cranberries. Serve and enjoy!
Notes
- Making this dish for your Thanksgiving menu? Line your baking sheet for foil or parchment paper for easy clean up!
- If your brussels sprouts are large quarter them instead of halving them. Roasted brussels sprouts are delicious when they are crispy and caramelized.
- For crispy vegetables make sure they are completely dry so they don't steam. Additionally, spread them out on the baking sheet in one even layer.
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