Place the biscuits in a single layer in the baking dish. Press them together to create one layer of dough.
Transfer to the oven and bake until golden, about 14-16 minutes.
While the biscuits bake, cook ground beef. Place a large heavy-duty skillet over medium heat. Add the ground beef, onion and bell peppers and cook, stirring occasionally until no longer pink, about 10 minutes.
Drain the excess fat from the skillet. Add the taco seasoning, salsa and rotel. Continue to cook, stirring occasionally, 3 to 4 minutes, set aside.
In a separate bowl, combine the sour cream and half the shredded cheddar cheese. Slice the jalapeño into thin slices.
Layer the ingredients evenly on top of the baked biscuit crust in this order; start with the ground beef onion-pepper-tomato mixture, sour cream-cheddar mixture, top with sliced jalapeños. Top with remaining cheese.
Bake until the cheese is bubbling and beginning to brown slightly, about 20 minutes. Let stand 10 minutes. Serve and enjoy!